as 101 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6761	Ossirene	AS101	IL Receptor , Caspase , Interleukin
	Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.		IL Receptor , Caspase , Interleukin
T1327	Nortriptyline hydrochloride	Desitriptyline HCl,EN-7048 hydrochloride,Desmethylamitriptyline hydrochloride,ELF-101 hydrochloride	Apoptosis , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Norepinephrine , Autophagy , Histamine Receptor , Drug Metabolite
	Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
T3678	Entrectinib	RXDX-101,NMS-E628	Trk receptor , ROS , ALK , Autophagy , ROS Kinase
	Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectini...		Trk receptor , ROS , ALK , Autophagy , ROS Kinase
T68973	EVT-101 free base
	EVT-101, also known as ENS-101, is an experimental medication which originated from Roche and is under development by Evotec AG for the treatment of major depressive disorder. It acts as a selective NMDA receptor subunit...
T35064	Viquidacin	NXL101,NXL-101,NXL 101
	Viquidacin ( NXL-101) is an oral/intravenous antibiotic that targets Gram-positive bacteria such as MRSA. In 2008, Novexel announced it had discontinued the development of Viquidacin (NXL 101).
T71231	VMY-1-101
	VMY-1-101 is a synthesized fluorescent CDK inhibitor. VMY-1-101 demonstrates potent CDK inhibitory activity, enhanced induction of G2/M arrest and modest apoptosis as compared to purvalanol B.
T75084	Foslevcromakalim
	Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].
T70509	INU-101
	INU-101 is an 11β-HSD1 inhibitor. In KKAy mice, ob/ob mice, and ZDF rats, oral administration of INU-101 led to enhanced insulin sensitivity and the lowering of the fasting level of glucose in the blood. INU-101 therefor...
T71290	EVT-101 HCl
	EVT-101 is a GluN2B antagonist, binding at the same GluN1/GluN2B dimer interface as ifenprodil but adopting a remarkably different binding mode involving a distinct subcavity and receptor interactions.
T80574	Becotatug	JMT-101	EGFR
	Becotatug (JMT-101) is an IgG1 antibody that targets EGFR and can be conjugated to Afatinib and Osimertinib, functioning as a synthetic antibody-drug conjugate (ADC) [1].		EGFR
T72056	KYN-101
	KYN-101 is a potent, selective synthetic antagonist of aryl hydrocarbon receptor (AHR) with IC50 of 22 nM in human HepG2 DRE-luciferase reporter assay and 23 nM in murine Hepa1 Cyp-luc assay.KYN-101 reverses IDO/TDO-medi...
T67948	OY-101
	OY-101, an orally active compound, serves as a potent and specific inhibitor of P-glycoprotein (P-gp). It has the capability to sensitize drug-resistant tumors and counteract tumor multidrug resistance efficiently. Compa...
T39347	RG-101
	RG-101 is a hepatocyte-targeted N-acetylgalactosamine conjugated oligonucleotide that functions as an antagonist for miR-122, an essential host factor in the replication of the hepatitis C virus (HCV).
T79120	WM-586		Histone Methyltransferase
	WM-586 is a covalent inhibitor of WDR5 that impedes the WDR5-MYC binding. It selectively reduces the interaction between WDR5 and MYC with an IC50 value of 101 nM, as determined by the HTRF assay [1].		Histone Methyltransferase
T80521	Caveolin-1 (82-101) amide (human, mouse, rat)	Caveolin-1 scaffolding domain peptide	c-Met/HGFR
	Caveolin-1 (82-101) amide (human, mouse, rat), also known as Caveolin-1 scaffolding domain peptide, mitigates aging-related detrimental alterations in various organs and inhibits tyrosine kinases [1].		c-Met/HGFR
T81490	PHI-101
	PHI-101, an orally active FLT3 inhibitor, effectively overcomes resistance associated with numerous drug-resistant mutations. It potently suppresses both single activating FLT3 mutations (ITD or TKD mutants) and inhibits...
T28542	Rivoglitazone HCl	CI-1037,CI1037,CS011,CS-011,CI 1037
	Rivoglitazone, also known as CI-1037; CS-011; DE-101; R-119702; Rivo, is a peroxisome proliferator-activated receptor γ agonist (PARPγ agonist) potentially for the treatment of type 2 diabetes. Rivoglitazone has been sho...
T70899	Vidofludimus hemicalcium	4sc-101 hemicalcium,SC12267 hemicalcium,4sc-101 hemicalcium ; SC12267 hemicalcium
	Vidofludimus hemicalcium (4sc-101; SC12267) is an orally active compound that acts as a dihydroorotate dehydrogenase (DHODH) inhibitor and serves as a novel modulator of the farnesoid X receptor (FXR). This immunomodulat...
T68866	Ceftolozane
	Ceftolozane, also known as FR-264,205 and CXA-101; is an antibiotic drug from the cephalosporin family, approved for the treatment of infections with gram-negative bacteria, or gram-positive bacteria. Ceftolozane is of g...
T76523	HCV Core Protein (107-114)
	HCV Core Protein (107-114), identified as the binding site within the region 101-118, is a minimally immunogenic fragment of the primary linear HCV core regions. This segment, comprising two residues that vary between ge...